Last updated: 11/24/2009

Angioplasties were originally performed by dilating the blood vessel with the introduction of larger and larger stiff catheters through the narrowed space. The complications that resulted from this approach led researchers to develop ways to open the...

vessel with smaller devices. As of 2003, the catheters used to perform angioplasties contain balloons that are inflated to widen the vessel, and stents (thin collapsed tubes made of wire mesh) to provide structural support for the vessel. Lasers may be used to help break up the plaque or fat deposits. Some catheters are equipped with spinning wires or drill tips to clean out the plaque.

Angioplasty may be performed while the patient is sedated or anesthetized, depending on which vessels are involved. If a percutaneous transluminal coronary angioplasty (PTCA) is to be performed, the patient is sedated so that he or she can report discomfort and cough if asked to do so. PTCA procedures are performed in cardiac catheterization laboratories with sophisticated monitoring devices. If angioplasty is performed in the radiology department's angiographic suite, the patient may be sedated for the procedure while a nurse monitors the patient's vital signs. Angioplasties performed by vascular surgeons are done in an operating room or specially designed vascular procedure suite.

Typically, patients are given anticoagulant (blood thinning) medications prior to the procedure to assist in the prevention of thromboses (blood clots), even though these drugs may slow down the sealing of the entry point into the vein. Patients may also be given calcium blockers and nitrates to reduce the risk of vascular spasm. The procedure is performed using fluoroscopic guidance and contrast media. Since the decision to perform angioplasty may have been made following a diagnostic angiogram, the patient's sensitivity to iodinated contrast media is likely to be known. The procedure may then require the use of non-ionic contrast agents.

The patient's skin is cleansed with an antiseptic solution at the site where the surgeon will insert the catheter and other equipment, and the area is protected with a sterile drape. Although many angioplasties are performed by puncturing the vessel through the skin, others are done by surgically exposing the site of entry. Direct view of the vessel's puncture site aids in monitoring damage to the vessel or excessive bleeding at the site. After the vessel has been punctured and the guidewire introduced, a fluoroscope is used to monitor the small amounts of contrast media that have been injected. This technique allows the surgeon to see the guidewire's movement through the vessel. If the fluoroscope has a feature called "roadmap," the amount of contrast media injected is greater in order to define the full route the guidewire will take. The fluoroscopy system then superimposes subsequent images over the roadmap while the physician moves the guidewire along the roadmap to the destination.

When the surgeon reaches the location of the stenosis, he or she inflates the balloon on the catheter that has been passed along the guidewire. The size of the balloon and the duration of its inflation depend on the size and location of the vessel. In some cases, the surgeon may also use a stent, which is opened or expanded inside the blood vessel after it has been guided to the proper location. The blood vessel may be widened before, during, or after the stent has been opened up. In cases where the vessel is tortuous (twisted) or at intersections of vessels, a graft may be necessary to strengthen the walls of the blood vessel. Stents, grafts, and balloon dilation may all be used together or separately. Sometimes radiation is used when a stent is placed.

After the surgeon has widened the blood vessel, he or she verifies its patency by using fluoroscopy and contrast media to produce an angiogram, by using intravascular ultrasound, or by using both techniques. After the imaging studies have been completed, the surgeon removes the equipment from the blood vessel and closes the puncture site.