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Last updated: 11/24/2009
HLA typing either by serologic (blood fluid) or DNA methods is reported as the phenotype for each HLA loci tested. The antibody screen test is reported as the percentage of panel reactive antibodies (PRA). The percent PRA is the number of wells reactive...
with the patient's serum expressed in percent. The crossmatch is reported as compatible or incompatible.
Tissue typing results for both donors and recipients and antibody screen results for recipients are submitted to the United Network for Organ Sharing (UNOS) database. The database searches all regional donors that are ABO-compatible for an HLA-identical match. If none is found, the database searches the national database for ABO compatible donors and scores the match. A point system is used based upon several parameters, including the number of matching HLA loci, the length of time the recipient has been waiting, the recipient's age, and the PRA score.
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The human leukocyte antigen test, also known as HLA, is a test that detects antigens (genetic markers) on white blood cells. There are four types of human leukocyte antigens: HLA-A, HLA-B, HLA-C, and HLA-D.
The HLA test is used to provide evidence of tissue compatibility typing of tissue recipients and donors. It is also an aid in genetic counseling and in paternity testing.
From http://www.lifesteps.com/gm/Atoz/ency/human_leukocyte_antigen_test.jsp
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